This meeting will present initial submissions for RFP that extends the Polymorphisms Markup Language (PML-2). This is a continuation of the PML-1 initiative that will extend this data exchange format into new areas of DNA polymorphism data handling.

The CSAR Finalization Task Force (FTF) will be chartered at this meeting.

The meeting focused on the SNP working group, issuing the RFP for the PML-2 (next generation of PML).

The CSAR specification was also presented in revised form to the Architecture Board and was passed.

The meeting focused on the SNP working group, preparing the RFP for the PML-2 (next generation of PML).This encluded:

• enhancements to PML-1 that may be necessary (e.g., genotype and haplotype components)
• a generic data model for phenotype information, suitable for representing raw and/or aggregated phenotype data
• components that capture causal relationships between DNA level and phenotype level information, including experimental details

The meeting focused on the SNP working group, evaluating the current status of PML (Polymorphic Markup Language), and preparing for the PML-2 (next generation of PML).

• FTF for Single Nucleotide Polymorphisms created

• FTF for Life Sciences Analysis Engine created

• W3C Workshop on Semantic Web in Life Sciences

• Adopted specifications: Single Nucleotide Polymorphisms and Life Sciences Analysis Engine

• Life Sciences Information Day

• Presentations of several recent submissions

• Presentation of the first revised submissions against Life Sciences Analysis Engine.

• Presentation of the joint initial submissions against Single Nucleotide Polymorphisms.

• Presentation of Revised Submission against LSR RFP-13 "Life Sciences Identifiers".

  Request to vote-to-vote and a vote to recommend an adoption - both passed. The Architecture Board also approved the specification. The DTC (domain task committee) started an electronic vote on it with the result expected in the middle of March.

• Election: Richard Scott from De Novo Pharmaceuticals Ltd was elected as a new LSR co-chair.

• Presentations of Initial Submissions against LSR RFP-18 "Life Sciences Analysis Engine".

• Presentations of Revised Submission against LSR RFP-13 "Life Sciences Identifiers".

• Updates by CNRS of initial submission against LSR RFP-14 "Biochemical Pathways".

• Presentations of Initial Submissions against LSR RFP-14 "Biochemical Pathways".

• Presentations of Revised Submission against LSR RFP-8 "Chemical Structure Access and Representation" (CSAR).

• An RFP for Single Nucleotide Polymorphisms was issued: lifesci/2003-06-01.

• An RFP for Chemical Compound Collections was issued: lifesci/2003-06-02.

• Initial Submissions against LSR RFP-13 "Life Sciences Identifiers" presented: lifesci/2003-06-03.

• A new version of MAGE (v1.1), containing only a couple of changes, has been recommended for adoption (the OMG voting process has started).

• Issuing an RFP for Single Nucleotide Polymorphisms was postponed (because of thr air traffic regulations). A draft still available for comments as document lifesci/2003-02-01.

• Vote to recommend CSAR Revised submission.

• New RFP "Life Science Identifiers" issued.
• New RFP "Gene Expression Query service" issued.
• New RFP "Life Sciences Analysis Engine" issued.

• Martin Senger (EBI) was elected as a new LSR co-chair replacing resigned Karl Konerth.

• Deadlines for Biochemical Pathways RFP were extended (LOI - July 28, 2003, Initial submissions - August 18, 2003)

• New working group "Simgle Nucleotide Polymorphisms", chaired by Tokia Kano (JBIC, Olympus Optical), was created.

• Successful joint meeting with the I3C.

• The Objects in Bio- & Chem-Informatics 2002 Conference (18-19 November)

• Voting on adoption of the revised submission against LSR RFP-8 "Chemical Structure Access & Representation (CSAR)"

• Revising drafts of RFPs for Gene Expression Identifiers and Query Service to prepare them to be issued at the Burlingame meeting

• Reviewing and revising the LSR Roadmap (Strategic Plan)

• Formalizing the liaison relationship with the I3C

• Evaluated the revised submission against LSR RFP-8 "Chemical Structure Access & Representation (CSAR)"

• Issued a new RFP for Biochemical Pathways

• Revised new draft RFPs for Gene Expression Identifiers and Query Service

• Reviewing and revising the LSR Roadmap (Strategic Plan)

• Presentation of revised submission against LSR RFP-8 "Chemical Structure Access & Representation (CSAR)"

• Extended the initial submissions deadline for the Chemical Sample Management RFP to 9 September 2002 (Letters of Intent are due 16 August).

• Extended the initial submissions deadline for the Laboratory Activities Broker RFP to 28 October 2002 (Letters of Intent are due 28 September).

• Drafted new RFPs for:
  • Gene Expression Identifier and Query Service
  • Biochemical Pathways

• Extablished a new Working Group for Biochemical Pathways; Steve Chervitz and Scott Markel, Co-Chairs

• Drafted first version of liaison agreement between OMG/LSR and the I3C.

• Extended the initial submissions deadline for the Laboratory Activities Broker RFP to 3 June 2002. Potential submitters are very welcome!

• Issued the Chemical Sample Management RFP. Potential submitters are very welcome!

• The Gene Expression joint revised submission was unanimously recommended by the LSR DTF.